EFFECTS OF LOW LEVEL LASER THERAPY (LLLT) BIOSTIMULATION ON GCF LEVELS OF SCLEROSTIN IN SURGICAL MANAGEMENT OF INTRABONY DEFECTS

Aim: To evaluate the effects of low level laser therapy (LLLT) biostimulation following open flap debridement (OFD) and correlate with GCF levels of sclerostin in intrabony defect management. Materials and methods: 30 patients with 2 and 3 wall intrabony defects were treated using LLLT biostimulation along with OFD (n=15) and OFD alone (n=15). Patients were recalled at 3 and 6 months to assess the changes in sclerostin levels, Plaque index, Gingival index, Probing pocket depth, Clinical attachment level, Defect depth and gain in defect height. Results: Both test and control groups showed a statistically significant improvement in all clinical parameters, sclerostin biomarker levels and defect depth from baseline to 3 and 6 months. However, the test group had a statistically significant reduction in defect depth at 3 to 6 months and the sclerostin biomarker levels also showed a statistically significant correlation to defect depth at all-time intervals. Conclusion: Within limitations of the present study it can be concluded that LLLT has a greater benefit over OFD alone in intra bony defect regeneration as observed by progressive bone fill from 3 to 6 months.