Non-Hodgkin lenfomalı olgularda standart prognostik faktörlerin 50 ve 60 yaş üstü-altı için değerlendirilmesi ve pik yaşı

OBJECTIVES Recently prognostic factors have gained importance in determining treatment decision in non-Hodgkin lymphomas (NHL). In this study PFs were examined in NHL patients. METHODS The records of 225 NHL patients (131 males; 94 females; mean age 51 years) applying to our hospital between January 2001 and April 2004 were evaluated retrospectively. Age, sex, histologic type, localization of disease, bulky tumor, extranodal involvement, involvement of liver, lung, spleen, bone marrow, presence of B symptoms, ECOG-PS, stage, IPI were investigated as PFs. Patients were divided into two groups according to two age cut-off values (60 years and 50 years). Thus subgroups were compared with respect to these PFs. RESULTS Peak ages were 61-70 (23. 6% of patients), and then 51-60 (19.6%). IPI and ECOG-PS were significantly worse for older subgroups in both age groups (IPI; p