A therapeutic composition for cartilage and method of use thereof.

A therapeutic composition for cartilage comprising a mixture of components of chondrocytes isolated and expanded or differentiated from a host, and thrombin and a fibrinogen matrix containing fibrinogen, wherein the thrombin is used in the amount of 0.01 to 50 IU / ml, wherein the fibrinogen matrix contains 0.01 mg / ml to 20 mg / ml collagen and 0.01 mg / ml to 20 mg / ml of hyaluronic acid, wherein the matrix fibrinogen contains 20 mg / ml to 200 mg / ml fibrinogen.