Abstract 212: Hypertrophic Cardiomyopathy Mutations With Opposite Effects on ß-myosin Biomechanics Show Similar Structural and Biomechanical Phenotypes in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (hipsc-cms)

Alison Schroer,Guanghyun Jung,Kristina B. Kooiker,Arjun S. Adhikari,Linda Song,Chao Liu,Kathleen M. Ruppel,Sean M. Wu,Beth L. Pruitt,James A. Spudich,Daniel Bernstein

Abstract 212: Hypertrophic Cardiomyopathy Mutations With Opposite Effects on ß-myosin Biomechanics Show Similar Structural and Biomechanical Phenotypes in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (hipsc-cms)

2019

Alison Schroer
Guanghyun Jung
Kristina B. Kooiker
Arjun S. Adhikari
Linda Song
Chao Liu
Kathleen M. Ruppel
Sean M. Wu
Beth L. Pruitt
James A. Spudich
Daniel Bernstein

Introduction: Hypertrophic cardiomyopathy (HCM) is the most prevalent heritable cardiovascular disease, commonly caused by mutations in beta cardiac myosin heavy chain (βMYH). We have measured the ...

Keywords:

Cardiology
Phenotype
Cell biology
Myosin
Internal medicine
Induced pluripotent stem cell
Biology
Hypertrophic cardiomyopathy
hipsc cms

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations