MBL and L-ficolin components of the complement activation lectin pathway in schizophrenia

Abstracts / Molecular Immunology 44 (2007) 3909–3994 P16MBLandL-ficolincomponentsofthecomplementactivationlectin pathway in schizophrenia Karine R. Mayilyan a , b , Anders Krarup a , Armen F. Soghoyan c ,Thomas Hartung d , Robert B. Sim aa MRC Immunochemistry Unit, Department of Biochemistry,Oxford University, South Parks Road, Oxford OX1 3QU, UK b Institute of Molecular Biology, Armenian National Academyof Sciences, 7 Hasratyan St., Yerevan 375014, Armenia c Yerevan State Medical University, Health Ministry of Arme-nian, 2 Koryun St., Yerevan 375025, Armenia d EuropeanCommission,JointResearchCentre,EuropeanCen-tre for the Validation of Alternative Methods, 21020 Ispra, Italy Schizophrenia is a severe and chronic mental illness knownas “one of the most debilitating and baffling mental ill-nesses.” Recent meta-analysis studies have linked infectiousagents to schizophrenia. Particularly, accumulating evidencesuggests that prenatal exposure to infection contributes to theetiology of schizophrenia. Adversity in