Ficolin

Ficolins (Fi+Col+Lin) are a group of oligomeric lectins with subunits consisting of both collagen (Col)-like long thin stretches and fibrinogen (Fi)-like globular domains with lectin (Lin) activity usually specific for N-acetylglucosamine (GlcNAc). Like collectins (Col+lectin) such as mannan-binding lectin, ficolins are secreted, lectin-type pattern recognition receptors, and similarly activate the lectin pathway of complement activation. Ficolins (Fi+Col+Lin) are a group of oligomeric lectins with subunits consisting of both collagen (Col)-like long thin stretches and fibrinogen (Fi)-like globular domains with lectin (Lin) activity usually specific for N-acetylglucosamine (GlcNAc). Like collectins (Col+lectin) such as mannan-binding lectin, ficolins are secreted, lectin-type pattern recognition receptors, and similarly activate the lectin pathway of complement activation.