An Efficient Synthesis of Enantiomerically Pure (R)-(2-Benzyloxyethyl)oxirane from (S)-Aspartic Acid

Jeffrey A. Frick,John B. Klassen,Andreas Bathe,Jill M. Abramson,Henry Rapoport

An Efficient Synthesis of Enantiomerically Pure (R)-(2-Benzyloxyethyl)oxirane from (S)-Aspartic Acid

1992

Jeffrey A. Frick
John B. Klassen
Andreas Bathe
Jill M. Abramson
Henry Rapoport

A 3-step synthesis of the title compound from (S)-aspartic acid is described. The overall yield of this process is 65% and the enantiomeric purity (ep) of the product is greater than 99%

Keywords:

Aspartic acid
Ether
Dicarboxylic acid
Organic chemistry
Enantiomer
Chemistry
short paper

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