Significant hemolysis is not required for thrombosis in paroxysmal nocturnal hemoglobinuria
2019
Paroxysmal nocturnal hemoglobinuria (PNH), a rare hematological condition, presents with hemolytic or thrombotic symptoms. PNH stem cells arise due to somatic mutations in the phosphatidylinositol glycan A gene in bone marrow stem cells, resulting in loss of the glycosylphosphatidylinositol anchor
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