Transmission and Suppression of Avian Influenza Virus

2018 
The growth of AIV is possible with supply of minerals from aeolian desert dust, as cofactors of enzymes, and thus the blockage of the aeolian desert dusts to the poultry farmhouse is important to suppress the enzymatic activity of AIV. South Georgia of Subantarctic Islands may be the source of Continental AIV, so that Continental AIV can become endemic within the local bird population when surrounding environments are close to Subantarctica of South Georgia. There are food webs in sequence of aquatic virus, bacteria, phytoplankton, zooplankton, krill, fish and squid while penguins feed on the fish or squid infected by mutant virus to generate LPAI after an incubation period. When migratory birds move to the Continents, HPAI can spread in the Continents due to low UV-B radiation, enough feed of rice, wheat, corn, wetland, and mineral-enriched desert dust. The clean room is equipped with air washers to remove aeolian dusts and migratory birds feces from working personnel and equipments, heaters to keep the pasteurisation of ultra-high temperature at 135°C for 1 - 2 seconds to inactivate AIV, humidifier to keep wet state above 65% relative humidity for weak virus activity, and the UV-C lamps (254 nm) to finally inactivate AIV. Since AIV doesn’t like the high salinity and high relative humidity, seawater is blanketed as sprayer to maintain high salinity (>20 ppt) and high relative humidity (>65%) from the top to the bottom of the poultry farmhouses for suppression of AIV transmission from infected aeolian dust coming from outside.
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