New Technologies and Tissue Repair and Regeneration (2): Other Biotherapeutic Technologies

Fibroblast growth factor (FGF) is a highly conserved polypeptide in biological evolution. It has been found that 23 FGF family members have high amino acid sequence homology. FGF has a wide range of biological effects on tissue cells derived from mesoderm and neuroectoderm. FGF promotes cell proliferation, migration, survival, and differentiation through FGF receptor (FGFR); participates in embryonic development, damaged tissue repair, neovascularization, stem cell proliferation and differentiation, nerve regeneration, calcium and phosphorus metabolism, etc.; plays an important role in wound repair, cardiovascular system diseases, nervous system diseases, and osteochondral regeneration; and have important clinical application value and broad market prospects.