Mesenchymal stem cells alleviate liver injury induced by chronic-binge ethanol feeding in mice via release of TSG6 and suppression of STAT3 activation

Yue-Meng Wan,Zhi-qiang Li,Qiong Zhou,Chang Liu,Men-Jie Wang,Hui-Xin Wu,Yun-Zhen Mu,Yue-Feng He,Yuan Zhang,Xi-Nan Wu,Yu-Hua Li,Zhi-Yuan Xu,Hua-Mei Wu,Ying Xu,Jin-Hui Yang,Xiao-Fang Wang

Mesenchymal stem cells alleviate liver injury induced by chronic-binge ethanol feeding in mice via release of TSG6 and suppression of STAT3 activation

2020

Yue-Meng Wan
Zhi-qiang Li
Qiong Zhou
Chang Liu
Men-Jie Wang
Hui-Xin Wu
Yun-Zhen Mu
Yue-Feng He
Yuan Zhang
Xi-Nan Wu
Yu-Hua Li
Zhi-Yuan Xu
Hua-Mei Wu
Ying Xu
Jin-Hui Yang
Xiao-Fang Wang

Background Mesenchymal stem cells (MSCs) are a population of pluripotent cells that might be used for treatment of liver disease. However, the efficacy of MSCs for mice with alcoholic hepatitis (AH) and its underlying mechanism remains unclear.

Keywords:

Cancer research
Mesenchymal stem cell
Liver disease
Liver injury
STAT3
Ethanol
Immunology
Biology
Population
Alcoholic hepatitis
Bone marrow
Necrosis
Stem cell
Pharmacology

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