Highly Sensitive Detection for Cocaine Using Aptamer Modified Molybdenum Disulfide/Gold Nanoparticles Microarray

The detection of cocaine based on aptamer modified molybdenum disulfide@gold nanoparticles (MoS2@AuNPs) nanosheet array immobilized on aminated slides was developed. Cocaine was detected using fluorescence energy resonance transfer between MoS2@AuNPs and aptamer modified with Cy5. The method had a detection limit of 0.19388 nM for cocaine.