Pharmacokinetic/pharmacodynamic analysis of voriconazole against Candida spp. and Aspergillus spp. in allogeneic stem cell transplant recipients

AbstractObjective:To evaluate the adequacy of different dosing regimens of voriconazole for the prophylaxis of invasive candidiasis and aspergillosis in adult allogeneic stem cell transplant recipients (ASCTRs) by means of population pharmacokinetic (PK) modelling and simulation.Methods:ASCTRs recei