Diffuse large B cell lymphoma of the cervix with rectal involvement.

Primary non-Hodgkin lymphoma (NHL) of the genital tract is a rare finding accounting for less than 1% of all extra-nodal disease, with that of the cervix accounting for 0.2–0.6% (Chan et al., 2005). Most patients present at a mean age of 46 with vaginal bleeding, a large, bulky cervix on exam, and without the common B symptoms of lymphoma. Cervical cytology is not always helpful as the disease originates from the cervical stroma (Chan et al., 2005). Approximately 70% are diagnosed at Ann Arbor stage I, 22% at stage II, and 8% stage III and above. To date, approximately 120 cases of primary extra-nodal cervical lymphoma have been reported. Diffuse large B-cell lymphoma (DLBCL) subtype is most commonly found at a rate of 30% (Anagnostopoulos et al., 2013). We describe an interesting case by virtue of the unique presentation of this disease and the extent of pelvic organ involvement.