Characterization of the phenotype of human eosinophils and their progenitors in the bone marrow of healthy individuals

Eosinophils are important innate effector cells that protect the host against invading multicellular parasites, although they also play a deleterious role in allergic diseases. The earliest committed progenitor cell for eosinophils was identified to be positive for both CD34 and IL-5Ra. However,