Contribution of P62 to the Phenotype Transition of Coronary Arterial Myocytes from Mice Lacking CD38 Gene

 Animal models for atherogenic changes in coronary arterial wall or CAMs were produced, and primary cell culture of CAMs, Western blot analysis, and confocal microscopy of autophagic and dedifferentiation markers were conducted as we described previously (J Cell Mol Med. 2014; 18: 2165-2175).  Cell cycle analysis and proliferation rate determination were performed as described in previous studies (Plos One 2015; 10: D119506)