Revisiting Sodium Hypochlorite Pentahydrate (NaOCl·5H2O) for the Oxidation of Alcohols in Acetonitrile without Nitroxyl Radicals

Tsunehisa Hirashita,Yuto Sugihara,Shota Ishikawa,Yohei Naito,Yuta Matsukawa,Shuki Araki

Revisiting Sodium Hypochlorite Pentahydrate (NaOCl·5H2O) for the Oxidation of Alcohols in Acetonitrile without Nitroxyl Radicals

2018

Tsunehisa Hirashita
Yuto Sugihara
Shota Ishikawa
Yohei Naito
Yuta Matsukawa
Shuki Araki

Sodium hypochlorite pentahydrate (NaOCl·5H 2 O) is capable of oxidizing alcohols in acetonitrile at 20 °C without the use of catalysts. The oxidation is selective to allylic, benzylic, and secondary alcohols. Aliphatic primary alcohols are not oxidized.

Keywords:

Aldehyde
Oxidizing agent
Acetonitrile
Alcohol oxidation
Organic chemistry
Sodium hypochlorite
Nitroxyl
Alcohol
Ketone
Chemistry
Allylic rearrangement

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations