Knockdown of Bone Morphogenetic Proteins Type 1a Receptor (BMPR1a) in Breast Cancer Cells Protects Bone from Breast Cancer-Induced Osteolysis by Suppressing RANKL Expression

Yang Liu,Ran-Xi Zhang,Wei Yuan,Hou-Qing Chen,Dong-Dong Tian,Hao Li,Xiao Jiang,Zhong-Liang Deng,Yang Wang

Knockdown of Bone Morphogenetic Proteins Type 1a Receptor (BMPR1a) in Breast Cancer Cells Protects Bone from Breast Cancer-Induced Osteolysis by Suppressing RANKL Expression

2018

Yang Liu
Ran-Xi Zhang
Wei Yuan
Hou-Qing Chen
Dong-Dong Tian
Hao Li
Xiao Jiang
Zhong-Liang Deng
Yang Wang

Background/Aims: Bone morphogenetic proteins (BMPs) and BMP receptors widely participate in osteolytic metastasis of breast cancer, while their role in tumor-stro

Keywords:

Bone metastasis
Bone morphogenetic protein
Breast cancer
BMPR1A
Biochemistry
RANKL
Metastasis
Cancer research
Receptor
Osteolysis
Biology
Bone morphogenetic protein receptor
Osteoclast
Cancer cell
Bone marrow

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