prophylactic and therapeutic of allergic, autoimmune and infectious with compounds based monosaccharides disease treatment.

The use in the manufacture of a medicament for the treatment of an infectious disease, an autoimmune disease or an allergic condition by monotherapy (i.e. in the absence of exogenous antigen), of one or more compounds having the formula: (See formula) and pharmaceutically acceptable salts thereof, wherein X is a member selected from the group consisting of -O- and -NH-; R 1 and R 2 are each a member independently selected from the group consisting of acyl (C2-C24); R 3 is a member selected from the group consisting of -H and -PO3R 11 R 12 wherein R 11 and R 12, each a member selected independently from the group consisting of -H and (C1 C4); R 4 is a member selected from the group consisting of -H, -CH3 and -PO3R 13, R 14, R 13 and R 14, each a member selected independently from the group consisting of -H and (C1-C4); and Y is a residue of formula: (See formula) wherein the subscripts n, m, p and q are each independently an integer of 0 to 6; R 5 is a (C2-C24) acyl group; R 6 and R 7 are members independently selected from the group consisting of H and CH3; R 8 and R 9 are independently selected from the group consisting members of H, OH, (C1-C4), -PO3H2, -OPO3H2, -SO3H, -OSO3H, -NR 15 R 16, -SR 15, - CN, -NO2, -CHO, -CO 2 R 15, -CONR 15 SR 16, -PO3R 15 R 16, -OPO3R 15 R 16, -SO 3 R 15 and -OSO3R 15, R 15 and R 16, each member independently selected from the group consisting of H and (C1-C4); and Z is -O- or -S-; with the proviso that when R 3 is -PO3R 11 R 12, R 4 is other than -PO3R 11 3R 14.