Influence of advanced recipient and donor age on the outcome of corneal transplantation

AIMS The aims of this study were to examine the influence of advanced recipient and donor age on the long term outcome of corneal transplantation. METHODS Records of 1036 penetrating corneal grafts in recipients aged ⩾80 years at surgery (defined as the elderly subset) and 8092 donor corneas used for transplantation were obtained from the Australian Corneal Graft Register database. Kaplan–Meier graft survival plots were compared using log rank statistics. RESULTS Elderly recipients constituted 15% of the recipient pool. The major indication for corneal transplantation in the elderly was bullous keratopathy. Graft survival fell with increasing recipient age (p CONCLUSIONS Elderly graft recipients fared less well after corneal transplantation than did younger recipients, but outcomes in terms of long term graft survival and visual rehabilitation were still good. Donor age did not affect graft survival.