Abstract 15660: Propranolol Inhibits Late Sodium Current in Long-QT Syndrome Type 3 Human Induced Pluripotent Stem Cell-drived Myocyte Model

Backgound: Long-QT syndrome type 3 (LQT3) is caused by gain-of-function mutations in SCN5A, encoding the α subunit of the cardiac voltage-gated sodium channel. LQT3 patients present bradycardia and...