Influence of chitosan-tripolyphosphate nanoparticles on thermosensitive polymeric hydrogels: structural organization, drug release mechanisms and cytotoxicity

Kelli Cristina Freitas Mariano,Mônica Helena Monteiro do Nascimento,Samyr M. Querobino,Estefânia Vangelie Ramos Campos,Jhones Luiz de Oliveira,Fabiano Yokaichiya,Margareth K.K.D. Franco,Carlos Alberto-Silva,Eneida de Paula,Christiane Bertachini Lombello,Renata de Lima,Leonardo Fernandes Fraceto,Daniele Ribeiro de Araujo

Influence of chitosan-tripolyphosphate nanoparticles on thermosensitive polymeric hydrogels: structural organization, drug release mechanisms and cytotoxicity

2019

Kelli Cristina Freitas Mariano
Mônica Helena Monteiro do Nascimento
Samyr M. Querobino
Estefânia Vangelie Ramos Campos
Jhones Luiz de Oliveira
Fabiano Yokaichiya
Margareth K.K.D. Franco
Carlos Alberto-Silva
Eneida de Paula
Christiane Bertachini Lombello
Renata de Lima
Leonardo Fernandes Fraceto
Daniele Ribeiro de Araujo

AbstractChitosan-tripolyphosphate (CS-TPP) nanoparticles containing naproxen (NPX) were dispersed in poloxamer (PL) as unique (PL407) or binary (PL407-PL403) systems. Nanoparticles presented diamet...

Keywords:

Organic chemistry
Nanoparticle
Materials science
Self-healing hydrogels
Drug
Cytotoxicity
Chitosan
Chemical engineering
drug release
Naproxen
structural organization
Poloxamer

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