Hydrofunctionalization of alkenols triggered by the addition of diverse radicals to unactivated alkenes and subsequent remote hydrogen atom translocation

Diverse anti-Markovnikov hydrofunctionalization of alkenols triggered by the addition of S-, P-, and C-centered radicals to alkenes followed by intramolecular 1,5(6)-hydrogen atom transfer (HAT) with remote α-C–H bonds of alcohols has been developed. The strategy simultaneously realized the hydrofunctionalization of alkenes and remote alcohol oxidation. This mild and versatile method allows for direct access to valuable sulfonyl-, phosphonyl-, and malonate-substituted ketones or aldehydes from a wide range of alkenols.