Novel approaches to patient recruitment and data integration

Case Studies 3 and 4: Observational Studies Linking Patient Surveys with Pharmacy Claims from Express Scripts Study Objective: To understand factors related to medication adherence Design Overview: Observational studies with direct-to-patient surveys, linked with pharmacy claims ♦ 1 study designed as non-interventional ♦ 1 study designed as interventional (assessed impact of intervention on adherence in addition to outcomes of interest below) Common Outcomes of Interest: ♦ Medication adherence ♦ Treatment experience ♦ Patient satisfaction ♦ Reasons for switching or discontinuing medication Challenges (Table 3): ♦ Identification and recruitment of patients ♦ Collection of a variety of outcomes of interest from a combination of sources Key Considerations: ♦ Identifying patients for whom we have access to pharmacy claims ♦ HIPAA waiver status