Caveolar Uptake and Endothelial-Protective Effects of Nanostructured Lipid Carriers in Acid Aspiration Murine Acute Lung Injury

Matina Kardara,Sophia Hatziantoniou,Aggeliki Sfika,Aliki G. Vassiliou,Elena A. Mourelatou,Christina Μagkou,Apostolos Armaganidis,Charalambos Roussos,Stylianos E. Orfanos,Anastasia Kotanidou,Nikolaos A. Maniatis

Caveolar Uptake and Endothelial-Protective Effects of Nanostructured Lipid Carriers in Acid Aspiration Murine Acute Lung Injury

2013

Matina Kardara
Sophia Hatziantoniou
Aggeliki Sfika
Aliki G. Vassiliou
Elena A. Mourelatou
Christina Μagkou
Apostolos Armaganidis
Charalambos Roussos
Stylianos E. Orfanos
Anastasia Kotanidou
Nikolaos A. Maniatis

Purpose Nanostructured lipid carriers (NLC), nanosized phospholipids/triglyceride particles developed for drug delivery, are considered biologically inactive. We assessed the efficacy of unloaded NLC as experimental treatment for acute lung injury (ALI).

Keywords:

Drug delivery
Thrombin
Nanomedicine
Lung
Biochemistry
Chemistry
Triglyceride
lung injury
pharmacology toxicology

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