Influence of a polymorphism IL1B gene in the response of rheumatoid arthritis and ankylosing spondylitis patients treated with infliximab

María José Morales Lara,Pablo Conesa-Zamora,V Santaclara,Daniel Torres-Moreno,Francisco Pedrero,J. Moreno Morales,V Cogolludo

Influence of a polymorphism IL1B gene in the response of rheumatoid arthritis and ankylosing spondylitis patients treated with infliximab

2010

María José Morales Lara
Pablo Conesa-Zamora
V Santaclara
Daniel Torres-Moreno
Francisco Pedrero
J. Moreno Morales
V Cogolludo

Cytokines such as IL1 are central mediators of joint inflammation in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS) and polymorphism in IL1 has been associated with disease susceptibility and severity.

Keywords:

Inflammation
Ankylosing spondylitis
Infliximab
Immunology
Rheumatoid arthritis
Interleukin 1 family
Physical therapy
Spondylitis
Disease
Medicine
in patient
Polymorphism (computer science)
Diabetes mellitus
Gene

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