Primitive Sca-1 positive bone marrow HSC in mouse model of aplastic anemia: A comparative study through flowcytometric analysis and scanning electron microscopy

Self-renewing Hematopoietic Stem Cells (HSCs) are responsible for reconstitution of all blood cell lineages. Sca-1 is the “stem cell antigen” marker used to identify the primitive murine HSC population, the expression of which decreases upon differentiation to other mature cell types. Sca-1