СЕКРЕЦИЯ ФАКТОРА НЕКРОЗА ОПУХОЛИ АЛЬФА ЭОЗИНОФИЛАМИ КРОВИ ПРИ РАКЕ ТОЛСТОГО КИШЕЧНИКА С ТКАНЕВОЙ ЭОЗИНОФИЛИЕЙ

We analyzed in vitro secretion of TNFα by peripheral blood eosinophil granulocytes in patients with colon cancer according to the presence of tumor-associated tissue eosinophilia. In colon cancer with tissue eosinophilia, an increase in basal and r-IL-5-induced in vitro secretion of TNFα by blood eosinophils was detected. It was shown that in patients with colon cancer, regardless of the presence of tissue eosinophilia, the levels of basal and r-IL-5-induced secretion of TNFα by eosinophil granulocytes in vitro were comparable.