Agonist Activation of F-Actin-Mediated Eosinophil Shape Change and Mediator Release Is Dependent on Rac2

Paige Lacy,Lian Willetts,John Dongil Kim,Andrea Lo,Bon Lam,E. MacLean,Redwan Moqbel,Marc E. Rothenberg,Nives Zimmermann

Agonist Activation of F-Actin-Mediated Eosinophil Shape Change and Mediator Release Is Dependent on Rac2

2011

Paige Lacy
Lian Willetts
John Dongil Kim
Andrea Lo
Bon Lam
E. MacLean
Redwan Moqbel
Marc E. Rothenberg
Nives Zimmermann

Background: Tissue recruitment and activation of eosinophils contribute to allergic symptoms by causing airway hyperresponsiveness and inflammation. Shape changes and mediator relea

Keywords:

Respiratory burst
Eosinophil
Inflammation
Rac GTP-Binding Proteins
Agonist
Immunology
Eosinophil peroxidase
Cell biology
Platelet-activating factor
Mediator
Biology

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