Microbobines et RMN en phase solide

This PhD thesis, at the interface between chemistry and physics, uses Solid State Nuclear Magnetic Resonance (ssNMR) for both exploiting diversity of materials and developing new easy-to-implement methodologies. ssNMR has proved to be really efficient to study materials and especially their interface by precisely characterising chemical environment of studied nuclei [1]. However, the main drawback of this technique is its lack of sensitivity, each analysis requiring 30 to 400 mg of sample. Such an amount is particularly difficult to obtain for sol-gel thin-film layers or for biological studies like Kidney stones. In order to solve this issue, the MACS (Magic Angle Coil Spinning) technique has been recently developed [2]. It consists of a micro-scaled coil surrounding a capillary containing the sample. Only 30 to 100 µg of material is necessary. As the microcoil is placed inside the usual solid state NMR rotor, no probe modification is needed. [1] C. Bonhomme, C. Gervais, and D. Laurencin, “Recent NMR developments applied to organic–inorganic materials,” Progress in Nuclear Magnetic Resonance Spectroscopy, vol. 77, pp. 1–48, Feb. 2014. [2] D. Sakellariou, G. L. Goff, and J.-F. Jacquinot, “High-resolution, high-sensitivity NMR of nanolitre anisotropic samples by coil spinning,” Nature, vol. 447, no. 7145, pp. 694–697, Jul. 2007.