Suppression of NANOG Induces Efficient Differentiation of Human Embryonic Stem Cells to Pancreatic Endoderm

2012 
ObjectiveA challenge in using human embryonic stem cells (hESCs) as the source of surrogate β cells is the establishment of methods that could effectively direct their differentiation into functional β cells. The aim of this study was to assess the effect of NANOG gene suppression in differentiating
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