[Steroid metabolism in primates. XVII. Isolation of 17alpha-hydroxy-pregnenolone from adrenal venous blood of the baboon (Papio hamdryas)].

: 17alpha-Hydroxypregnenolone (3beta,17alpha-dihydroxy-5-pregene-20-one) was isolated from adrenal venous blood of male healthy baboons and identified by paper chromatography, thin layer chromatography and infrared spectrometry. In 6 animals the concentration in adrenal venous blood (16--70 mug/100ml) and the secretion rate (2--5 mug/h/kg body weight) have been estimated. The results demonstrate the secretion of 17alpha-hydroxypregnenolone by the baboon adrenal.