Synthesis and neurotropic activity of N-benzylimides of 2-oxo-1-oxaspiro-4,5(4,4)decane(nonane)-3,4-dicarboxylic acids

N-benzylimides containing new combinations of bonds of the known types between spiro-γ-lactone and succinimide nuclei have been synthesized via the condensation of diethyl esters of 2-oxo-1-oxaspiro-4,5(4,4)-decane(nonane)-3,4-dicarboxylic acids with benzylamine. The class of spirocondensed heterocyclic systems includes comparatively low-toxicity compounds capable of inhibiting the deamination of serotonin (5-HT) and potentiating the effects of tryptamine and 5-hydroxytryptophan.