Abstract P3-S7.16 Table 1 Association between Lactobacillus colonisation in the vagina and acquisition of bacterial vaginosis (BV)

Background Prevention of HIV and other STDs using vaginal microbicides must be safe. Colposcopy has not been shown to predict microbicide safety; therefore a more sensitive method is needed in safety evaluations of these vaginal products. The use of optical coherence tomography (OCT) has shown increased sensitivity to tissue injury over colposcopy in animal models. We describe a randomised double blind clinical trial using OCT to detect epithelial changes and injury related to vaginal microbicide use.