Assessment of 5-methylcytosine and 5-hydroxymethylcytosine technologies in contrived ctDNA-like samples.

Eun-Ang Raiber-Moreau,James Hadfield,Darren Hodgson,Marilou Wijdicks

Assessment of 5-methylcytosine and 5-hydroxymethylcytosine technologies in contrived ctDNA-like samples.

2020

Eun-Ang Raiber-Moreau
James Hadfield
Darren Hodgson
Marilou Wijdicks

e15585Background: Epigenomic changes to DNA are early driving events in tumorigenesis and are specific markers of the tumour and its microenvironment. Cell-free DNA that is released from the tumour...

Keywords:

Biochemistry
5-Hydroxymethylcytosine
5-Methylcytosine
Pathology
Medicine
Cancer research
Epigenomics
Carcinogenesis
DNA

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