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Darren Hodgson

AstraZeneca

71

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Concordance of BRCA mutation detection in tumor versus blood, and frequency of bi-allelic loss of BRCA in tumors from patients in the phase III SOLO2 trial

2021 Gynecologic Oncology
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An adaptive, biomarker-directed platform study of durvalumab in combination with targeted therapies in advanced urothelial cancer.

2021 Nature Medicine
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Analysis of mutation status and homologous recombination deficiency in tumors of patients with germline BRCA1 or BRCA2 mutations and metastatic breast cancer: OlympiAD.

2021 Annals of Oncology
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Assessment of 5-methylcytosine and 5-hydroxymethylcytosine technologies in contrived ctDNA-like samples.

2020 Journal of Clinical Oncology
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998PDAnalysis of tumour samples from SOLO1: Frequency of BRCA specific loss of heterozygosity (LOH) and progression-free survival (PFS) according to homologous recombination repair deficiency (HRD)-LOH score

2019 Annals of Oncology
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Abstract 1747: Both somatic and germline BRCA mutations show high degree of bi-allelic loss in breast and ovarian cancers

2019 Cancer Research
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Correlation of circulating tumor DNA (ctDNA), tissue-based genomic profiling and clinical efficacy in the biomarker directed Ph1b trial in metastatic bladder cancer (BISCAY).

2019 Journal of Clinical Oncology
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Dual-specificity protein phosphatase DUSP4 regulates response to MEK inhibition in BRAF wild-type melanoma.

2019 British Journal of Cancer
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PD-L1 and immune infiltrates are differentially expressed in distinct subgroups of gastric cancer

2019 OncoImmunology
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1936PAnalysis of BRCA genes and homologous recombination deficiency (HRD) scores in tumours from patients (pts) with metastatic breast cancer (mBC) in the OlympiAD trial

2019 Annals of Oncology
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