Critical evaluation of Cbx7 downregulation in primary colon carcinomas and its clinical significance in Chinese patients.
2015
Background
CBX7 is a Polycomb group protein that shows variable expression changes in various cancers that are often contradictive. A mouse knockout experiment has validated the tumor suppressor role in carcinogenesis. The purpose of this study is to verify the tumor suppressor role of Cbx7 in human colon carcinomas (CC).
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