Evaluation of hybrid porous biomimetic nano-hydroxyapatite/polyamide 6 and bone marrow-derived stem cell construct in repair of calvarial critical size defect.

AbstractNano-hydroxyapatite/polyamide 6 (n-HA/PA6) composite scaffolds were prepared by a combined method of phase separation and particle leaching processing technique. The porous matrices were seeded with allogenic bone marrow-derived stem cells (BMSCs) and implanted in the critical-size calvarial