Inhibition of stimulated Jurkat cell adenosine 3′,5′-cyclic monophosphate synthesis by the immunomodulatory compound HR32577Abbreviations: PGE2, prostaglandin E2; FKN, forskolin; CTX, cholera toxin; cAMP, adenosine 3′,5′-cyclic monophosphate; IBMX, 3-isobutyl-1-methylxanthine; NCA, niclosamide; FCCP, carbonyl cyanide p-trifluoromethoxyphenyl hydrazone; DHO-DH, dihydroorotate dehydrogenase; IL-2, interleukin-2; and HBSS, Hanks’ balanced salt solution.
2001
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