IBMX (3-isobutyl-1-methylxanthine), like other methylated xanthine derivatives, is both a: IBMX (3-isobutyl-1-methylxanthine), like other methylated xanthine derivatives, is both a: As a phosphodiesterase inhibitor, IBMX has IC50 = 2–50 μM and does not inhibit PDE8 or PDE9.