Detection of Marker Chromosome in the Abortion Material; Does It Reflect the Karyotype of the Pregnancy Lost Tissue or the Maternal Decidual Tissue? Case Report

ABS TRACT De ter mi na ti on of the ori gin of the mar ker chro mo so mes is very dif fi cult and requires ef fort. Eva lu a ti on of the mar ker chro mo so mes of the preg nancy lost tis su e co uld be the most dif fi cult one as the con ta mi na ti on with ma ter nal de ci du al cells comp li ca tes this pro cess. Con ven ti o nal cyto ge ne tic tech ni qu es and flu o res cen ce in si tu hybri di za ti on tech ni qu e or mo re ad van ced mo le cu lar tech ni qu es are pre fer red to de ter mi ne the ori gin of the se chro mo so mes. In this re port, the study for iden ti fi ca ti on of the ori gin of an abor ti on ma te ri al de ri ved from the pri mary tis su e cell cul tu re, with a 47,XX,+mar(15) kar yoty pe was pre sen ted, by using an ef fec ti ve al go rith mic ap pro ach which en ded with ge noty ping. The re sult of the ge noty ping was in for ma ti ve, sin ce the as su med abor ti on ma te ri al ac tu ally be lon ged to the mot her’s de ci du al tis su e. This bri ef study re minds the ef fi ci ent al go rith mic ap pro ac hes to the de ter mi na ti on pro cess of the mar ker chro mo so mes of the abor ti on ma te ri al.