Keratokonusta Korneal Kollajen Çapraz Bağlama Sonuçlarinin Değerlendirilmesi Corneal Collagen Cross-Linking for Treatment of Keratoconus

Summary Background: The aim of this study was to assess the results of corneal collagen cross-linking (CXL) with riboflavin using ultraviolet-A light for the treatment of keratoconus. Methods: Thirty seven eyes of 37 patients with progressive keratoconus were included in this retrospective study. The corneal epithelium was removed manually within the central 8-9 mm diameter area. A solution of 0.1% riboflavin was applied to the cornea every 5 min for 30 min prior to irradiation. The cornea was irradiated with UV-A light. During the 30 min irradiation, drops of riboflavin solution were applied to the cornea at 5 min intervals. During the follow up period, we recorded the best spectacle-corrected visual acuity (BSCVA), manifest refraction and corneal topographic changes at 1 month, 3 and 6 months. Results: There was no statistically significant change in BSCVA (p>0.05). The preoperative mean BSCVA was 0.47±0.21 and the postoperative BSCVA was 0.47±0.19. Spherical equalant decreased by an average of 0.55 D (p<0.05). The mean K value decreased by 0.53 D. There was a statistically significant decrease in the mean K reading (p<0.05).