Anti-tumoral potential of a human granulysin-based, CEA-targeted cytolytic immunotoxin

Raquel Ibáñez-Pérez,Patricia Guerrero-Ochoa,Sameer Al-Wasaby,Rocío Navarro,Antonio Tapia-Galisteo,Diego De Miguel,Oscar Gonzalo,Blanca Conde,Luis Martínez-Lostao,Ramon Hurtado-Guerrero,Laura Sanz,Alberto Anel

Anti-tumoral potential of a human granulysin-based, CEA-targeted cytolytic immunotoxin

2019

Raquel Ibáñez-Pérez
Patricia Guerrero-Ochoa
Sameer Al-Wasaby
Rocío Navarro
Antonio Tapia-Galisteo
Diego De Miguel
Oscar Gonzalo
Blanca Conde
Luis Martínez-Lostao
Ramon Hurtado-Guerrero
Laura Sanz
Alberto Anel

ABSTRACTGranulysin is a protein present in the granules of human cytotoxic T lymphocytes (CTL) and natural killer (NK) cells, with cytolytic activity against microbes and tumors. Previous work demo...

Keywords:

Cancer research
Immunology
Granulysin
Cytotoxic T cell
CTL*
Cytolysis
Medicine
Immunotoxin
colon carcinoma
a protein

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