The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients.

Emelie Englund,Bart Reitsma,Ben C. King,Astrid Escudero-Esparza,Sioned Owen,Akira Orimo,Marcin Okroj,Lola Anagnostaki,Wen Guo Jiang,Karin Jirström,Anna M. Blom

The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients.

2015

Emelie Englund
Bart Reitsma
Ben C. King
Astrid Escudero-Esparza
Sioned Owen
Akira Orimo
Marcin Okroj
Lola Anagnostaki
Wen Guo Jiang
Karin Jirström
Anna M. Blom

The human Sushi Domain-Containing Protein 4 (SUSD4) was recently shown to function as a novel inhibitor of the complement system, but its role in tumor progression is unknown.

Keywords:

CA15-3
Sushi domain
Pathology
Cancer
Cancer research
Complement Inactivator Proteins
Medicine
Stem cell
Cell migration
Tumor progression
Complement system
complement inhibitor
Breast cancer
Metastasis
Cancer cell

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