CD34 expression does not correlate with immunophenotypic stem cell or progenitor content in human cord blood products.

Sruthi Mantri,Andreas Reinisch,Beruh T. Dejene,Deirdre J. Lyell,David DiGiusto,Rajni Agarwal-Hashmi,Ravindra Majeti,Kenneth I. Weinberg,Matthew H. Porteus

CD34 expression does not correlate with immunophenotypic stem cell or progenitor content in human cord blood products.

2020

Sruthi Mantri
Andreas Reinisch
Beruh T. Dejene
Deirdre J. Lyell
David DiGiusto
Rajni Agarwal-Hashmi
Ravindra Majeti
Kenneth I. Weinberg
Matthew H. Porteus

The CD34+ compartment of human cord blood contains a range of HSPC immunophenotypes, among which the Lin−CD34+CD38+CD127+ CLP is rare. There is no correlation between the frequencies of CD34+ cells and immunophenotypic HSC in umbilical cord blood products.

Keywords:

Cord blood
CD34
Biology
Stem cell
Progenitor
Pathology

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