AMPK Activation in Dorsal Root Ganglion Suppresses mTOR/p70S6K Signalling and Alleviates Painful Radiculopathies in Lumbar Disc Herniation Rat Model

Study Design.Animal experiment: a rat model of lumbar disc herniation (LDH) induced painful radiculopathies.Objective.To investigate the role and mechanism of AMP-activated protein kinase (AMPK) in dorsal root ganglia (DRG) neurons in LDH-induced painful radiculopathies.Summary of Background Data.Ov