Prevalence and heterogeneity of androgen receptor splice variants and intra-AR structural variation in patient with castration-resistant prostate cancer.

Luc Dirix,Bram De Laere,Pieter-Jan van Dam,Tom Whitington,Markus Mayrhofer,Emanuela Henao Diaz,Gert Van den Eynden,Jean Vandebroek,Jurgen Del-Favero,Steven Van Laere,Henrik Grönberg,Johan Lindberg

Prevalence and heterogeneity of androgen receptor splice variants and intra-AR structural variation in patient with castration-resistant prostate cancer.

2017

Luc Dirix
Bram De Laere
Pieter-Jan van Dam
Tom Whitington
Markus Mayrhofer
Emanuela Henao Diaz
Gert Van den Eynden
Jean Vandebroek
Jurgen Del-Favero
Steven Van Laere
Henrik Grönberg
Johan Lindberg

11530Background: Androgen receptor splice variant 7 (AR-V7) is linked to a priori resistance to abiraterone acetate and enzalutamide. However, AR-V7 negativity does not necessarily indicate respons...

Keywords:

Androgen receptor
Prostate cancer
Structural variation
Cancer research
Castration
Pathology
Medicine
Enzalutamide
Abiraterone acetate
in patient
castration resistant
splice

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