Using 2D correlation and multivariate analysis combined with plasmonic effects to expand the use of Raman microspectroscopy in biomedical applications

We show that Surface Enhanced Raman spectroscopy (SERS) combined with 2D correlation and multivariate analysis provides considerable progress in using Raman microspectroscopy for cutting edge biomedical research applications such as treatment delivering in cancer living cells, the diagnosis of retina neuroinflamed tissue and the study of elastic properties of single DNA molecules.