Tooth Regenerative Therapy: Tooth Tissue Repair and Whole Tooth Replacement

Oral function and associated health issues are impaired by irreversible dental problems, including dental caries and periodontal disease. Tooth regenerative therapy for tissue repair and whole tooth replacement are novel treatment approaches with the potential to fully recover tooth function. The dental tissue repair method uses stem cells and cytokines but not artificial materials to promote odontogenesis. Whole tooth replacement therapy as a form of bioengineered organ replacement is regarded as an important model system for the development of this concept. This article reviews recent findings and technologies underpinning tooth regenerative therapy.