CHARACTERIZATION OF NANOCURCUMINOID FROM ETHANOL EXTRACT OF Curcuma Xanthorrhiza RHIZOME LOADED BY CHITOSAN AND ALGINIC AND ITS ANTIOXIDANT ACTIVITY TEST

Curcuminoid is the main compound found in the Curcuma xantorrhiza rhizome. C. xantorrhiza plant which inIndonesia is known as temulawak is an herbal plant that is traditionally used to cure hepatitis, increase stamina, andas an anti-cholesterol. To enhance the stability, solubility and activity of the curcuminoid, should be developed intoa product nanoparticle. The purpose of this study was to characterize nanocurcuminoids from ethanol extracts fromthe C. xantorrhiza rhizome loaded by chitosan and alginic acid, and its antioxidant activity test. Thenanocurcuminoid formulation method uses ionic gelation. Chitosan nanocurcuminoid is made by mixingcurcuminoid solution and chitosan solution, then adding sodium tripolyphosphate (Na-TPP). Meanwhile, alginicnanocurcuminoids are made by mixing a solution of curcuminoids and alginic acid solutions, which are then addedto calcium ions.